Table 5.
Whole-brain results for rest-state functional connectivity outside networks of interest
| Seed | Brain region, PCL-R score | MNI coordinates | Cluster size (voxels), t value |
|---|---|---|---|
| Regression results: main cortical networks of interest | |||
| DMN | |||
| Facet 4/antisocial | |||
| PCC | Bilateral primary visual cortex | −1, −81, 12 | 195, 4.17 |
| FPN | |||
| Total PCL-R | |||
| R IPS | Left inferior temporal/fusiform gyrus | −43, −45, −15 | 87, −4.52 |
| R dlPFC | Left lingual gyrus | −22, −54, −3 | 97, −5.11 |
| Factor 1 | |||
| L IPS | Right cerebellum | 20, −81, 42 | 81, −4.46 |
| R IPS | Left inferior temporal-occipital/fusiform gyrus | −40, −69, −21 | 98, −4.07 |
| L dlPFC | Right middle occipital gyrus | 26, −87, 15 | 95, −4.08 |
| R dlPFC | Left primary visual cortex | −4, −87, −9 | 103, −4.84 |
| R dlPFC | Left ventral occipital cortex | −19, −78, −12 | 94, −4.26 |
| Factor 2 | |||
| R dlPFC | Left ventral occipital cortex | −25, −72, −21 | 176, 4.28 |
| R dlPFC | Left cerebellum | −25, −54, −33 | 128, 4.41 |
| Facet 1/interpersonal | |||
| R IPS | Left fusiform gyrus/inferior temporal cortex | −43, −54, −24 | 176, −4.49 |
| R IPS | Right inferior frontal gyrus | 50, 9, 24 | 139, −4.37 |
| CON | |||
| Total PCL-R | |||
| L aIfO | Right cuneus extending to lingual gyrus | 2, −81, 18 | 135, −4.09 |
| R aIfO | Right caudate extending to subgenual anterior cingulate | 11, 18, −3 | 89, 4.66 |
| Factor 1 | |||
| R aIfO | Right primary visual cortex, (cluster extends bilaterally) | 2, −93, 3 | 344, −4.39 |
| R aIfO | Right precentral gyrus | 44, −6, 63 | 101, −4.89 |
| Facet 1/interpersonal | |||
| R aIfO | Bilateral primary visual cortex | −4, −96, 9 | 758, −5.89 |
| Facet 2/affective | |||
| R aIfO | Right lingual gyrus | 5, −93, 12 | 77, −4.02 |
| dACCmsFC | Right lingual gyrus | 20, −84, 33 | 104, −4.31 |
| L aIfO | Left postcentral gyrus extending to precentral gyrus | −49, −12, 42 | 72, −3.90 |
| Facet 4/antisocial | |||
| dACC/msFC | Right cuneus | 20, −87, 33 | 73, −4.53 |
| Regression results: comparison networks | |||
| AN | |||
| Factor 1 | |||
| Left Heschl's gyrus | Right mid-insula/posterior insula | 41, −6, 12 | 84, −4.18 |
| Facet 3/lifestyle | |||
| Right Heschl's gyrus | Left parahippocampal gyrus | −25, −30, −12 | 129, 3.97 |
Significant clusters outside the networks of interest for psychopathy scores (total PCL-R, Factor 1, and Factor 2) from the regression analyses. All regression results reported were significant after controlling for age, SUD, race, and IQ (cluster-corrected pFWE = 0.05; Holm–Bonferroni corrected, each p < 0.05).