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. 2015 Apr 15;35(15):6153–6164. doi: 10.1523/JNEUROSCI.4571-14.2015

Figure 5.

Figure 5.

Infusion of RG108 directly into mPFC prevents escalation in alcohol intake in PD rats. A, Black bars indicate mean values (± SEM) of rats before drug injection. Gray bars indicate mean values (± SEM) of rats after drug injection. Ctl refers to Control rats. Infusion of RG108 into mPFC prevents the increased alcohol consumption observed in the PD compared with control rats. B, RG108 does not modify locomotor activity. White bars indicate mean values (± SEM) of rats treated with vehicle. Black bars indicate mean values (± SEM) of rats treated with RG108. #p < 0.05, control versus PD rats. *p < 0.05, vehicle versus RG108.