Table 4.

RG108 treatment does not regulate the expression cacna1a, syt1, syt2, cacna1l, Slc8a2, and wnk2 in the Amg, NAc, and Hipp^a

	CTL/vehicle		CTL/RG108		PD/vehicle		PD/RG108
	Fold change	SEM	Fold change	SEM	Fold change	SEM	Fold change	SEM
Amg
Cacna1a	1.01	0.05	−1.02	0.07	−1.13	0.04	−1.12	0.05
Syt1	1.01	0.04	1.01	0.04	−1.05	0.05	−1.05	0.05
Syt2	1.02	0.07	−1.09	0.09	−1.24	0.11	−1.12	0.05
Cacna1l	1.01	0.06	1.10	0.06	1.10	0.12	1.05	0.06
Slc8a2	1.02	0.08	1.19	0.10	1.56	0.23	1.26	0.11
wnk2	1.01	0.05	1.08	0.06	1.19*	0.05	1.32*	0.14
Hipp
Cacna1a	1.01	0.06	1.03	0.05	1.07	0.05	1.24	0.11
Syt1	1.01	0.04	1.15	0.03	1.25	0.05	1.09	0.08
Syt2	1.02	0.08	1.32	0.15	1.52*	0.13	1.50*	0.14
Cacna1l	1.01	0.07	1.00	0.06	1.11	0.11	1.18	0.11
Slc8a2	1.02	0.08	1.05	0.06	1.20*	0.06	1.17*	0.05
Wnk2	1.01	0.06	0.81	0.04	1.29*	0.16	1.01	0.05
NAc
Cacna1a	1.12	0.19	1.29	0.12	1.30	0.15	1.19	0.13
Syt1	1.09	0.17	1.19	0.09	1.12	0.09	1.02	0.07
Syt2	1.24	0.38	1.53	0.23	1.85	0.49	1.42	0.26
Cacna1l	1.02	0.08	−1.06	0.08	1.00	0.10	0.88	0.09
Slc8a2	1.02	0.07	−1.07	0.07	−1.03	0.08	−1.22	0.07
Wnk2	1.01	0.06	−1.02	0.06	1.02	0.06	−1.19	0.05

^amRNA levels (fold change) of cacna1a, syt1, syt2, cacna1l, Slc8a2, and wnk2 in the Amg, NAc, and Hipp of control and PD rats treated with vehicle or RG108.

*p < 0.05, control versus PD rats.