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. 2015 Feb 20;8:63–79. doi: 10.2147/PGPM.S52845

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© 2015 Richer et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Frequency of selected molecular alterations in lung adenocarcinomas and squamous cell carcinomas.

Notes: The frequency of selected molecular alterations as reported in The Cancer Genome Atlas for (A) lung adenocarcinomas (230 samples) and (B) squamous cell carcinomas (178 samples). Red represents gene amplification, blue represents homozygous deletion, green represents mutation, and a black triangle represents a gene fusion. This figure is adapted from an OncoPrint figure generated at http://www.cbioportal.org.¹²²

Abbreviations: TP53, tumor protein p53; EGFR, epidermal growth factor receptor; STK11, serine/threonine kinase 11; ALK, anaplastic lymphoma receptor tyrosine kinase; RET, ret proto-oncogene; ROS1, ROS proto-oncogene 1, receptor tyrosine kinase; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; PTEN, phosphatase and tensin homolog; CDKN2A, cyclin-dependent kinase inhibitor 2A; FGFR1, fibroblast growth factor receptor 1.