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. 2015 Feb 20;8:63–79. doi: 10.2147/PGPM.S52845

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© 2015 Richer et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Molecular alterations in lung adenocarcinomas with targeted therapeutic opportunities.

Abbreviations: RET, ret proto-oncogene; EGFR, epidermal growth factor receptor; mABs, monoclonal antibodies; TKI, tyrosine kinase inhibitor; ALK, anaplastic lymphoma receptor tyrosine kinase; KRAS, Kirsten rat sarcoma viral oncogene homolog; PI3K, phosphatidylinositol 3-kinases; LKB1, serine/threonine kinase 11; p53, tumor protein p53; Hsp90, heat shock protein 90; MTOR, mammalian target of rapamycin; MAPK, mitogen-activated protein kinase.