Table 1.
Clinical characteristics of the study subjects
| Factor | NW | OB | ||
|---|---|---|---|---|
| NW-NBP | NW-HTN | OB-NBP | OB-HTN | |
| Age (year) | 49.21 ± 8.95 | 49.90 ± 8.63 | 49.28 ± 8.73 | 48.16 ± 7.87 |
| Gender (M/F)# | 66(43/23) | 67(48/19) | 58(35/23) | 55(37/18) |
| BMI (kg/m2) | 22.50 ± 1.45 | 22.10 ± 1.65 | 28.02 ± 1.65ab | 28.52 ± 2.00ab |
| WC (cm) | 79.88 ± 6.51 | 81.36 ± 7.02 | 91.80 ± 7.29ab | 95.79 ± 5.76abc |
| WHR | 0.87 ± 0.05 | 0.89 ± 0.05a | 0.91 ± 0.06a | 0.95 ± 0.05abc |
| SBP (mmHg) | 119.26 ± 9.44 | 154.76 ± 11.39a | 125.97 ± 10.09ab | 159.89 ± 14.54ac |
| DBP (mmHg) | 75.89 ± 6.61 | 100.07 ± 7.51a | 77.97 ± 7.07b | 101.65 ± 11.46ac |
| UA (μmol/l) | 295.10 ± 72.89 | 332.22 ± 78.21a | 346.61 ± 68.96a | 387.85 ± 99.98ab |
| TG (mmol/l) | 1.39 ± 0.60 | 2.05 ± 1.15a | 2.05 ± 1.48a | 2.41 ± 1.02abc |
| TC (mmol/l) | 4.97 ± 0.92 | 5.38 ± 0.94a | 5.03 ± 0.82b | 5.25 ± 0.83 |
| LDL-C (mmol/l) | 2.70 ± 0.59 | 2.74 ± 0.58 | 2.80 ± 0.50 | 2.72 ± 0.49 |
| HDL-C (mmol/l) | 1.58 ± 0.40 | 1.41 ± 0.25 | 1.34 ± 0.28a | 1.33 ± 0.34a |
| FBG (mmol/l) | 5.38 ± 0.52 | 5.29 ± 0.54 | 5.60 ± 0.57ab | 5.47 ± 0.47 |
| FINS (pmol/l) | 9.54 ± 3.23 | 10.93 ± 3.07 | 14.47 ± 6.13ab | 16.13 ± 5.19ab |
| WBC (109 cells/l) | 5.25 ± 1.07 | 6.06 ± 1.17a | 5.90 ± 1.50a | 6.05 ± 1.50a |
| RBP4(μg /ml) | 50.97 ± 15.19 | 65.09 ± 17.09a | 49.76 ± 14.72b | 64.08 ± 18.86ac |
| HOMA-IR | 2.29 ± 0.85 | 2.60 ± 0.90a | 3.64 ± 1.71ab | 3.93 ± 1.34ab |
| HOMA-β | 109.83 ± 51.11 | 130.62 ± 46.54a | 145.83 ± 69.43a | 175.19 ± 80.73abc |
| Smoking (%)# | 32.8 | 37.0 | 33.6 | 33.6 |
| Drinking (%)# | 26.6 | 34.7 | 51.4ab | 51.4ab |
Data represent the means ± SD or frequency (percentage).
CTRP3, TG, FINS, HOMA-IR and HOMA-β were log-transformed prior to analysis.
#chi-squared test.
ap < 0.01 compared with NW-NBP.
bp < 0.01 compared with NW-HTN.
cp < 0.01 compared with OB-NBP.
NW, normal weight subject; OB, obese subject; NW-NBP, NW with normal blood pressure.
NW-HTN, NW with hypertension; OB-NBP, OB with normal blood pressure; OB-HTN, OB with hypertension.
BMI, body mass index; WC, waist circumference; WHR, waist-to-hip ratio.
SBP, systolic blood pressure; DBP, diastolic blood pressure.
UA, uric acid; TG, triglyceride; TC, total cholesterol.
LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.
FBG, fasting blood glucose; FINS, fasting plasma insulin; WBC,white blood cell.
HOMA-IR, HOMA-IR index; HOMA-β, HOMA β cell function index.