. 2015 Mar 4;15:114. doi: 10.1186/s12879-015-0815-1

Table 2.

Cytokine production by splenocytes of immunized mice after stimulation by ROP18 protein at 8-weeks post immunization ^*

Group (n = 3)	Cytokine production (pg/mL)				Proliferation (Stimulation Index) ^#
Group (n = 3)	IFN-γ	IL-2	IL-4	IL-10	ROP18	ConA
CAV-2-ROP18 (I)	914.26 ± 36.56^a	431.07 ± 28.94^a	197.29 ± 29.98^a	44.37 ± 38.54^a	4.87 ± 0.65^a	2.93 ± 0.43^a
CAV-2 (II)	44.28 ± 9.37^b	47.23 ± 7.59^b	52.65 ± 9.24^b	38.49 ± 5.48^a	0.23 ± 0.06^b	3.07 ± 0.19^a
PBS (III)	46.13 ± 10.27^b	52.60 ± 11.97^b	54.87 ± 9.45^b	41.36 ± 5.23^a	0.26 ± 0.10^b	2.81 ± 0.32^a
Blank Control (IV)	42.98 ± 6.76^b	51.45 ± 3.88^b	53.38 ± 5.97^b	40.63 ± 6.74^a	0.27 ± 0.07^b	2.84 ± 0.26^a

*Data are reported as mean ± SD.

^#Splenocytes from mice were collected 8-weeks after the immunization.

Values for IL-10 and IFN-γ are for 72 h, values for IL-2 and IL-4 are for 24 h.

Within each column, groups with different superscripts are different (P < 0.05).