Figure 2.

Comparison between simulations and MFA experiments. Comparison between selected simulated fluxes using molecular weights, thermodynamic penalties, and a combination of the two costs, and Metabolic Flux Analysis (MFA) data. Fluxes are normalized by glucose to glucose-6-phosphate conversion rates. X-axes values are kept constant for all plots. Reaction names are taken from the Ecoli iJR904 model [52]. Yellow boxes indicate Pentose Phosphate Pathway (PPP), blue indicates glycolysis, green indicates TCA cycle and red indicates other reactions