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. 2014 Sep 26;472(12):4006–4009. doi: 10.1007/s11999-014-3900-7

Table 1.

Sensitivity and specificity results

Results Alpha defensin-1 assay Culture Cell count Erythrocyte sedimentation rate C-reactive protein
Sensitivity 100% 69% 95% 50% 79%
(95% CI, 79%–100%) (95% CI, 43%–86%) (95% CI, 72%–99%) (95% CI, 29%–75%) (95% CI, 54%–93%)
p = 0.065 p = 0.239 p = 0.013 p = 0.067
Specificity 95% 88% 85% 80% 66%
(95% CI, 83%–99%) (95% CI, 72%–95%) (95% CI, 69%–94%) (95% CI, 63%–91%) (95% CI, 48%–80%)
p = 0.185 p = 0.112 p = 0.077 p = 0.065

P value is for comparison with the AD-1 assay.