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. 2015 Apr 15;12:10. doi: 10.1186/s12981-015-0052-0

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© Oluka et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Differences in log ₁₀ -transformed plasma nevirapine levels by genotype. Panel A, Log₁₀-transformed plasma nevirapine levels for each CYP2B6 516G>T genotype: GG, GT, and TT. Panel B, Log₁₀-transformed plasma nevirapine levels for each CYP2B6 983T>C genotype: TC and TT. Panel C, Log₁₀-transformed plasma nevirapine levels for each CYP2B6 phenotype (predicted from CYP2B6 516G>T and 983T>C genotypes). EM = extensive metabolizer, IM = intermediate metabolizer, SM = slow metabolizer.