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. 2015 Apr 15;6:171. doi: 10.3389/fimmu.2015.00171

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Copyright © 2015 Churlaud, Pitoiset, Jebbawi, Lorenzon, Bellier, Rosenzwajg and Klatzmann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phenotypic characterization of CD8⁺CD25⁺FOXP3⁺ Tregs (CD8⁺ Tregs) compared with CD8⁺CD25⁻FOXP3⁻effector CD8⁺ T cells (CD8⁺ Teffs) and with CD4⁺CD25⁺FOXP3⁺ Tregs (CD4⁺ Tregs) in female BALB/c mice. Representative histograms showing expression of CD103, CTLA-4, Ki-67, CD122, ICOS, and Bcl-2 in CD8⁺ Teffs (gray) and in CD8⁺ Tregs (black) compared to isotype control (white) are shown. Corresponding percentages in the overall population are shown. Individual values and mean ± SEM are shown.