Table 3.
Antibiotic usage for evaluable CABP patients treated in the ICU (n=138) and in general medical wards (n=256)
| Antibiotic therapya | ICU, n (%) | General medical ward, n (%) |
|---|---|---|
| Prior to ceftaroline fosamil (all antibiotics) | 120 (87.0) | 205 (80.1) |
| Glycopeptides | 55 (39.9) | 61 (23.8) |
| Other cephalosporins | 51 (37.0) | 96 (37.5) |
| Quinolones | 51 (37.0) | 68 (26.6) |
| Macrolides | 39 (28.3) | 64 (25.0) |
| Penicillins | 35 (25.4) | 40 (15.6) |
| Other antibioticsb | 73 (52.9) | 80 (31.3) |
| Concurrently with ceftaroline fosamil (all antibiotics) | 94 (68.1) | 167 (65.2) |
| Quinolones | 36 (26.1) | 52 (20.3) |
| Macrolides | 29 (21.0) | 65 (25.4) |
| Glycopeptides | 21 (15.2) | 20 (7.8) |
| Other cephalosporins | 13 (9.4) | 15 (5.9) |
| Penicillins | 8 (5.8) | 16 (6.3) |
| Other antibioticsb | 48 (34.8) | 72 (28.1) |
| Subsequent to ceftaroline fosamil (all antibiotics) | 60 (43.5) | 125 (48.8) |
| Quinolones | 20 (14.5) | 39 (15.2) |
| Penicillins | 8 (5.8) | 16 (6.3) |
| Other antibioticsb | 57 (41.3) | 105 (41.0) |
Notes:
a
These categories are not mutually exclusive, and patients may have received more than one antibiotic class. Data are only presented when >5% of patients in both locations of care were receiving a named antibiotic class.
b
Other antibiotics administered to patients included carbapenems, lincosamides, oxazolidinones, sulfa antibiotics, and tetracyclines, as well as other antibiotics that were not categorically defined.
Abbreviations: CABP, community-acquired bacterial pneumonia; ICU, intensive care unit.