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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: Pediatr Allergy Immunol. 2013 Jun 16;24(5):476–486. doi: 10.1111/pai.12095

Table 3. Eczema prevalence and severity are associated with poorer health outcomes and increased healthcare utilization.

Comorbid health condition No eczema Eczema P-value#
Freq Percent (95% CI) Freq Percent (95% CI)
Number of chronic conditions
None 54191 79.1 (78.4, 79.8) 6957 65.5 (63.3, 67.8) < 0.0001
1 9233 12.9 (12.3, 13.5) 1975 19.7 (17.8, 21.6)
2 2736 3.8 (3.5, 4.1) 558 5.3 (4.4, 6.3)
3-4 2156 2.9 (2.6, 3.2) 541 5.5 (4.4, 6.7)
5+ 864 1.3 (1.1, 1.6) 309 3.9 (2.8, 5.0)
Overall health
Excellent 46262 63.4 (62.4, 64.3) 5592 52.2 (49.9, 54.5) < 0.0001
Very good 15218 22.1 (21.3, 22.9) 2949 28.5 (26.4, 30.7)
Good 6314 11.5 (10.8, 12.2) 1329 13.5 (12.0, 15.1)
Fair 1195 2.6 (2.2, 3.0) 395 5.0 (3.8, 6.1)
Poor 197 0.4 (0.3, 0.6) 71 0.7 (0.4, 1.0)
Impaired sleep (nights per week)
0 nights 28199 64.3 (63.2, 65.3) 3471 57.4 (54.4, 60.4) < 0.0001
1-3 nights 14628 27.0 (26.1, 28.0) 2014 29.9 (27.2, 32.6)
4+ nights 4179 7.6 (7.1, 8.1) 651 10.8 (9.0, 12.7)
Healthcare utilization within the past 12 months
More services than most children same age 7812 11.2 (10.6, 11.8) 1999 20.7 (18.7, 22.7) < 0.0001
Seen a specialist 16390 21.3 (20.6, 2.1) 4111 37.4 (35.2, 29.6) < 0.0001
Number of health, mental, dental, therapy services used
1 of 5 11563 19.2 (18.4, 20.0) 1556 16.4 (14.9, 18.0) < 0.0001
2 of 5 39567 57.5 (56.5, 58.4) 4698 44.6 (42.4, 46.9)
3 of 5 15897 20.8 (20.1, 21.6) 3510 33.4 (31.2, 35.6)
4 of 5 2153 2.5 (2.3, 2.8) 576 5.5 (4.4, 6.6)
Comorbid health condition Mild or moderate eczema Severe eczema P-value#
Freq Percent (95% CI) Freq Percent (95% CI)
Number of chronic conditions < 0.0001
None 6726 66.9 (64.6, 69.2) 262 46.1 (36.8, 55.3)
1 1835 19.6 (17.6, 21.5) 148 22.1 (15.3, 28.8)
2 501 5.2 (4.2, 6.2) 57 6.7 (3.7, 9.6)
3-4 492 5.2 (4.0, 6.3) 52 10.9 (6.1, 15.8)
5+ 256 3.2 (2.2, 4.1) 57 14.2 (6.8, 21.7)
Overall health < 0.0001
Excellent 5429 54.1 (51.7, 56.4) 181 26.1 (18.6, 33.6)
Very good 2804 28.9 (26.7, 31.1) 163 24.1 (17.4, 30.8)
Good 1197 12.4 (11.0, 13.9) 141 28.2 (18.9, 37.5)
Fair 328 4.1 (3.0, 5.2) 67 16.9 (9.4, 24.4)
Poor 50 0.4 (0.2, 0.6) 22 4.5 (1.3, 7.8)
Impaired sleep (nights per week) 0.003
0 nights 3252 57.5 (54.3, 60.6) 229 54.6 (43.5, 65.8)
1-3 nights 1919 30.7 (27.9, 33.5) 97 21.0 (13.1, 28.9)
4+ nights 589 10.0 (8.2, 11.7) 62 22.2 (11.1, 33.3)
Healthcare utilization within the past 12 months
More services than most children same age 1786 19.3 (17.3, 21.3) 222 38.5 (29.8, 47.2) < 0.0001
Seen a specialist 3811 36.3 (34.1, 38.5) 322 51.3 (42.1, 60.5) 0.001
Number of health, mental, dental, therapy services used < 0.0001
1 of 5 1519 16.9 (15.3, 18.5) 47 11.4 (4.0, 18.9)
2 of 5 4526 45.4 (43.0, 47.7) 188 34.3 (25.8, 42.7)
3 of 5 3267 32.9 (30.6, 35.2) 257 38.6 (30.1, 47.1)
4 of 5 498 4.9 (3.9, 5.9) 84 15.7 (8.1, 23.4)
#

Rao-Scott chi-square test

Parental refusal to answer a particular question or response of “don't know” occurred for the questions pertaining to ever eczema in 79 (0.1%), eczema severity in 22 (0.2%), number of chronic conditions in 1 (0.0002%), overall health in 18 (0.01%), impaired sleep in 493 (1.1%), more services than most children the same age in 370 (0.3%), seeing a specialist in 96 (0.1%) and number of services used in 0 (0.0%), respectively.

Note: The proportional odds assumption was not met (Score test, P<0.01). Therefore, ordinal logistic regression was not used. Rather, all analyses of severity used binary logistic regression on dichotomized severe vs. mild-moderate disease. However, similar results were obtained when severity was dichotomized moderate-severe vs. mild.

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