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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: Pflugers Arch. 2000 Apr;439(6):829–837. doi: 10.1007/s004249900233

Fig. 4.

Fig. 4

A,B Transient plugging by 5.4- and 8.4-nm diameter dendrimer particles. A, B Effects of 5.4- and 8.4-nm diameter dendrimer particles, respectively. Γp record ensembles similar to those in Fig. 3. The time of acquisition for each record ensemble is shown at the top of each panel. The concentration for both 5.4- and 8.4-nm diameter particles was estimated at 109 particles/l. A The arrow in the ensemble recorded at 30 min indicates a slow transition probably resulting from dendrimer particle translocation through the NPCC. B The arrow shown at 20 s indicates the moment when the dendrimer particle plugged the NPCC. The arrows in the ensemble recorded at 1 min point to brief spikes of ion fluxes probably related to escape of ions through orifices between the dendrimer particles and the lining of the pore lumen. These orifices, however, were short-lived since the pore remained shut, and did not open after a 4-min exposure to the dendrimer particles. Conductance and time calibrations are shown at the top- and bottom-right corners, respectively