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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: Free Radic Biol Med. 2010 Jul 13;49(6):1119–1128. doi: 10.1016/j.freeradbiomed.2010.06.030

Fig. 2.

Fig. 2

The cytoplasmic tail of ICAM-1 increases GCL activity, but not enzyme subunit protein expression. (A) GCL activity measured at various time points after cellular treatment with AP or AP-ICAM peptide (normalized to vehicle). (B) GCL activity after cellular treatment with the AP-ICAM peptide plus BSO (normalized to AP-ICAM treatment alone). (C and D) Western blot and quantitation comparing levels of Gclc protein in cells at 6 h posttreatment with AP-ICAM or AP peptide. n=5, #p<0.001, experiments performed in quadruplicate, Western blots performed in triplicate.