Table 1.
Baseline characteristics of the 513 patients who received neoadjuvant chemotherapy followed by surgery
| Characteristic | No. of patients (%) |
|---|---|
| Median age (range, yr) | 42.4 (24-67) |
| < 35 | 87 (17.0) |
| ≥ 35 | 426 (83.0) |
| Histologic type | |
| Invasive ductal carcinoma | 487 (94.9) |
| Invasive lobular carcinoma | 26 (5.1) |
| Clinical tumor stage | |
| 1 | 21 (4.0) |
| 2 | 266 (51.9) |
| 3 | 187 (36.5) |
| 4 | 39 (7.6) |
| pT category | |
| 0 or is | 54 (10.5) |
| 1 | 190 (37.0) |
| 2 | 190 (37.0) |
| 3 | 59 (11.6) |
| 4 | 20 (3.9) |
| pN category | |
| 0 | 194 (37.8) |
| 1 | 154 (30.0) |
| 2 | 104 (20.3) |
| 3 | 61(11.9) |
| Type of surgery | |
| Breast conserving | 257 (50.1) |
| Mastectomy | 256 (49.9) |
| Estrogen receptor | |
| Negative | 242 (47.2) |
| Positive | 271 (52.8) |
| Progesterone receptor | |
| Negative | 324 (63.2) |
| Positive | 188 (36.6) |
| HER2 | |
| Negative | 328 (63.9) |
| Positive | 185 (36.1) |
| Ki-67 | |
| Low expression (< 15%) | 366 (71.3) |
| High expression (≥ 15%) | 147 (28.7) |
| Pathologic complete response | 54 (10.5) |