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. 2014 Sep 12;47(2):259–265. doi: 10.4143/crt.2013.230

Table 4.

Toxicity profiles in patients aged over 70 years

No. of episodes (%)
GP
XP
Grade 1-2 Grade 3-4 Total Grade 1-2 Grade 3-4 Total
Hematologic
 Anemia 8 (29.6) 6 (22.2) 14 (51.8) 1 (2.8) 0 1 (2.8)
 Neutropenia 2 (7.4) 2 (7.4) 4 (14.8) 6 (16.7) 2 (5.6) 8 (22.2)
 Thrombocytopenia 7 (25.9) 4 (14.8) 11 (40.7) 4 (11.1) 4 (11.1) 8 (22.2)
Non-hematologic
 Nausea 2 (7.4) 1 (3.7) 3(11.1) 0 2 (5.6) 2 (5.6)
 Vomiting 2 (7.4) 1 (3.7) 3(11.1) 1 (2.8) 1 (2.8) 2 (5.6)
 Anorexia 2 (7.4) 1 (3.7) 3 (11.1) 1 (2.8) 1 (2.8) 2 (5.6)
 Asthenia 3 (11.1) 1 (3.7) 4 (14.8) 0 3 (8.3) 3 (8.3)
 Stomatitis 0 0 0 1 (2.8) 1 (2.8) 2 (5.6)
 Diarrhea 0 0 0 0 0 0
 Neuropathy 0 0 0 0 0 0
 Nephropathy 0 0 0 0 0 0
 Hand-foot syndrome 0 0 0 1 (2.8) 3 (8.3) 4 (11.1)
 Infection 0 0 0 0 0 0

GP, gemcitabine-cisplatin; XP, capecitabine-cisplatin.