Table 6.

Univariate and Multivariate Logistic Regression Analyses of the Predictors of Reflux Esophagitis and Peptic Ulcer Disease

	Variables	Univariate analysis		Multivariate analysis
		OR (95% CI)	P-value	Adjusted OR (95% CI)	P-value
Reflux esophagitis	Male sex	2.964 (2.689–3.267)	< 0.001	2.403 (2.140–2.698)	< 0.001
	Body mass index ≥ 25 kg/m2	1.679 (1.553–1.814)	< 0.001	1.406 (1.290–1.533)	< 0.001
	Current smoker	1.962 (1.802–2.137)	< 0.001	1.430 (1.302–1.570)	< 0.001
	Age	0.993 (0.989–0.996)	< 0.001	0.995 (0.990–0.999)	0.013
	Heavy drinker	1.458 (1.231–1.728)	< 0.001
	K-BDI level ≥10	0.734 (0.605–0.889)	0.002
	BEPSI-K level ≥2.4	1.354 (1.199–1.528)	< 0.001
PUD	NSAID	1.978 (1.550–2.523)	< 0.001	2.080 (1.589–2.721)	< 0.001
	Age	1.026 (1.020–1.033)	< 0.001	1.042 (1.035–1.050)	< 0.001
	Current smoker	2.016 (1.732–2.347)	< 0.001	1.789 (1.509–2.122)	< 0.001
	Body mass index	1.087 (1.065–1.109)	< 0.001	1.068 (1.042–1.094)	< 0.001
	Male sex	2.079 (1.762–2.453)	< 0.001	1.718 (1.399–2.110)	< 0.001
	Atrophic/metaplastic gastritis	0.650 (0.564–0.749)	< 0.001	0.500 (0.424–0.590)	< 0.001
	Heavy drinker	1.852 (1.412–2.429)	< 0.001
	K-BDI level ≥ 10	0.677 (0.468–0.979)	0.038
	Antiplatelet agent	1.875 (1.474–2.384)	< 0.001

CI, confidence interval; OR, odds ratio; NSAID, nonsteroidal anti-inflammatory drug; K-BDI, Korean version of the Beck’s Depression Inventory; BEPSI-K, the Brief Encounter Psychosocial Instrument-Korean version; PUD, peptic ulcer disease.

Univariate and multivariate logistic regression analyses were performed and the significant results are highlighted in bold.

In peptic ulcer disease, the following parameters were excluded from the analysis, because the P-values from the Chi-square test were more than 0.05; BEPSI-K level ≥2.4 (P = 0.862), anticoagulant (P = 1.000).