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Effects of neostigmine on contractile activity in W/W v mice. (A) It shows a stomach from a W/W v mouse that was dissected to form a flat-sheet preparation (B). With no drugs present, peristaltic contractions were abnormal, consisting of 2–3 pulsatile contractions simultaneously over large areas of the antrum (C). Neostigmine increased the amplitude and duration of the train of pulsatile contractions (D–F).
