Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr;21(2):200–216. doi: 10.5056/jnm14120

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Korean Society of Neurogastroenterology and Motility

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 4. — Effects of cholinergic stimulation on electrical activity of the corpus. (A) Slow waves from corpus circular muscle under control conditions (Krebs-Ringer bicarbonate solution [KRB] perfusion) and after addition of carbachol (CCh; 100 nM). CCh depolarized resting membrane potential and increased the frequency of slow waves. (B) Slow waves from another corpus muscle are shown before (upper trace), during a period of electrical field stimulation (EFS; 5 Hz; 0.1 milliseconds pulses; middle trace), and after addition of atropine during EFS (100 nM; bottom trace). EFS enhanced the frequency of slow waves without significant change in resting membrane potential. (C) Slow waves recorded from corpus are shown in control conditions (top trace) after treatment with neostigmine (1 μM; middle trace), and after atropine was added in the presence of neostigmine (100 nM; bottom trace). (D) It shows a summary of the effects of neostigmine on slow wave frequency (numbers of muscles are shown above each test condition: asterisk (*) indicates P < 0.05 compared to control). Atropine, tetrodotoxin, and hexamethonium also reduced the elevation in slow wave frequency caused by neostigmine. Data are means ± SEM.