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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: EXS. 2006;(95):193–211. doi: 10.1007/3-7643-7417-9_15

Figure 3.

Figure 3

The distribution of NPY receptors in the normal and epileptic rat dentate gyrus. NPY receptor distribution of a normal adult rat (A) and an adult rat that has had severe continuous seizures (status epilepticus; B) are shown. The distributions appears similar regardless of the methods to induce status, and seizures last for 1 or more hours. Methods that are commonly used to induce status include the convulsant pilocarpine or kainic acid, or electrical stimulation. After status epilepticus, spontaneous repetitive seizures develop within weeks, and persist for the life of the animal (i.e., epileptogenesis occurs). For further explanation and references, see text.