Table III.

Changes from mean baseline at 3 and 6 months in MRI cartilage thickness variables

Region	Over 3 months			Over 6 months
	N	% Change	95% CI	N	% Change	95% CI
nwcMF	27	−2.1	(−4.4, 0.2)	28	0.0	(−2.7, 2.8)
nwMF	27	−0.9	(−2.1, 0.2)	28	1.1	(−0.4, 2.6)
ncMF	27	−1.3	(−2.6, 0.1)	28	0.6	(−1.3, 2.5)
nMF	27	−0.8	(−1.7, 0.1)	28	1.3	(−0.1, 2.6)
wcMF	27	−1.6	(−3.7, 0.5)	28	0.4	(−2.0, 2.8)
wMF	27	−1.0	(−2.5, 0.5)	28	1.2	(−0.2, 2.7)
cMF	27	−1.1	(−2.6, 0.4)	28	0.6	(−1.1, 2.3)
MF	27	−1.1	(−2.4, 0.1)	28	1.0	(−0.6, 2.5)
nwMT	27	0.7	(−2.3, 3.8)	28	−1.2	(−3.3, 1.0)
nMT	27	0.4	(−2.1, 2.9)	28	−0.5	(−2.9, 2.0)
wMT	27	0.8	(−2.0, 3.6)	28	−1.0	(−2.9, 0.9)
MT	27	0.3	(−2.0, 2.8)	28	−1.4	(−3.5, 0.8)
nwcMTF	27	−0.5	(−2.2, 1.3)	28	−0.4	(−2.3, 1.6)
ncMTF	27	−0.4	(−1.7, 1.0)	28	0.2	(−1.7, 2.0)
wcMTF	27	−0.4	(−2.0, 1.3)	28	−0.1	(−1.8, 1.6)
cMTF	27	−0.4	(−1.8, 1.0)	28	−0.3	(−1.9, 1.3)
nwcLF	27	−0.1	(−12, 0.9)	28	0.3	(−0.8, 1.5)
nwLF	27	0.7	(−0.5, 2.0)	28	0.3	(−1.0, 1.5)
ncLF	27	0.1	(−0.8, 1.1)	28	−0.1	(−1.3, 1.1)
nLF	27	0.8	(−0.4, 2.0)	28	−0.1	(−1.5, 1.3)
wcLF	27	0.0	(−1.1, 1.2)	28	0.4	(−0.7, 1.5)
wLF	27	0.5	(−0.8, 1.9)	28	0.2	(−1.0, 1.5)
cLF	27	0.2	(−1.1, 1.6)	28	−0.3	(−1.5, 0.9)
LF	27	0.7	(−1.0, 2.4)	28	−0.6	(−1.9, 0.9)
nwLT	27	−0.1	(−2.0, 1.8)	28	−1.2	(−2.4, 0.1)
nLT	27	0.7	(−0.4, 1.7)	28	−0.6	(−1.7, 0.5)
wLT	27	−0.2	(−2.3, 2.0)	28	−1.5	(−2.9, −0.2)
LT	27	1.1	(−0.1, 2.3)	28	−0.9	(−2.3, 0.6)
nwcLTF	27	−0.2	(−1.2, 0.9)	28	−0.1	(−1.0, 0.7)
ncLTF	27	0.3	(−0.5, 1.2)	28	−0.3	(−1.1, 0.5)
wcLTF	27	−0.1	(−1.2, 1.1)	28	−0.2	(−1.1, 0.6)
cLTF	27	0.6	(−0.5, 1.8)	28	−0.5	(−1.4, 0.4)

The mean and 95% CI estimates are from fitting ANOVA models to the log transformed data.

The ANOVA models include the baseline measure as a covariate.

The baseline is the geometric mean of the value at Visits 2a and 2b.

CIs are not corrected for multiple comparisons.

Legend for regions as detailed in Materials and methods section.