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. 2015 Apr 15;10(4):e0124366. doi: 10.1371/journal.pone.0124366

Fig 1. GLB1 increases expression in HGPIN and PCa.

Fig 1

(A) Gene expression was measured using the AQUA platform as described [20] in an initial multitissue prostate array. Epithelial GLB1 expression is significantly increased in HGPIN, primary prostate cancer and BPH compared to benign in both nuclear and cytoplasmic compartments (All p<0.001). For all tissue types, expression was 2–3 times greater in the nucleus than the cytoplasm (p<0.0001). (B) Tissue microarrays immunofluorescently stained Glb1 (red) primarily in the epithelium.