Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 15;11(4):e1005169. doi: 10.1371/journal.pgen.1005169

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Kyöstilä et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Fig 4 — (A) Axonal spheroids stain diffusely positive for LC3B. IHC LC3B, scale bar 100 μm. (B,C) The granular cores of the spheroids are positive for (B) ubiquitin (arrow) and (C) p62. IHC ubiquitin and p62, scale bars 20 and 100 μm, respectively. (D) Smooth axonal swellings in the cerebellar cortex contain ATG4D. Inset: control. IHC ATG4D, scale bar 100 μm. (E) Affected neurons show increased perinuclear granular LC3B positivity. Inset: control. IHC LC3B, scale bar 100 μm. (F) Neuronal vacuoles are partially LAMP2 positive (arrow) and partially negative (arrow head). Inset: control. IHC LAMP2, scale bar 20 μm.