Fig 2. Box plot of ATV plasma trough concentrations clustered according to the grade of hyperbilirubinemia (scored as grade 0, 1, 2, 3 or 4 based on total bilirubin concentrations below 1.3 mg/dL, between 1.3–1.9, 1.9–3.1, 3.1–6.1, or above 6.1 mg/dL, respectively).

*p<0.01 vs grade 0.