Table 2. Results of the NCAPG I442M and GDF8 Q204X association analyses.
Single marker analysis | 2 SNP model | 2 SNP interaction model | |||||||
---|---|---|---|---|---|---|---|---|---|
NCAPG I442M 1 | GDF8 Q204X 2 | NCAPG I442M 1 | GDF8 Q204X 2 | vs. 2 SNP model | |||||
a 3 | p-value | a 3 | p-value | a 3 | a 3 | p-value | p-value 4 | ||
RFI | -2.18 (0.49) | 0.13 x 10–4 | -3.30 (0.91) | 0.46 x 10–03 | -2.04 (0.47) | -3.07 (0.87) | 0.37 x 10–06 | 0.92 | |
FCR | -1.85 (0.50) | 0.12 x 10–03 | -1.99 (0.96) | 0.04 | -1.76 (0.50) | -1.79 (0.92) | 0.14 x 10–03 | 0.44 | |
dEI | 1.62 (0.70) | 0.03 | -1.09 (1.31) | 0.38 | 1.39 (0.74) | -1.11 (1.31) | 0.14 | 0.36 | |
ADG | 0.08 (0.02) | 0.45 x 10–05 | 0.06 (0.03) | 0.06 | 0.08 (0.02) | 0.06 (0.03) | 0.81 x 10–05 | 0.13 | |
Arg | 9.03 (2.35) | 0.19 x 10–03 | -6.20 (4.68) | 0.19 | 9.54 (2.34) | -8.78 (4.46) | 0.14 x 10–03 | 0.29 | |
C0 | 0.11 (0.09) | 0.26 | -0.73 (0.17) | 0.25 x 10–04 | 0.14 (0.09) | -0.77 (0.17) | 0.42 x 10–04 | 0.08 |
1 rs109570900
2 rs110344317
3 allele substitution effect (standard error) NCAPG 442M vs. 442I or GDF8 204X vs 204Q, respectively
4 p-value testing a model fitting both SNPs and their epistatic interaction vs. a model fitting both SNPs