Table 3. Linear age effects on functional and structural connectivity strength between the prefrontal cortex (PFC) and other brain regions.

Prefrontal and posterior regions connectivity at lobes level	Functional Network ß-value (p-value)	Structural Network ß-value (p-value)
PFC-Lateral Temporal	-0.144 (0.061)	0.287 (<0.001)* T
PFC-Medial Temporal	-0.103 (0.180)	0.281 (<0.001)*
PFC-Parietal	-0.198 (0.010)	0.102 (0.176)
PFC-Occipital	0.114 (0.144)	0.113 (0.137)
PFC-Motor & Sensory	-0.119 (0.124)	0.229 (<0.001)*

Standardized ß-values and their corresponding p-values are listed.

*p < 0.01 (Bonferroni corrected threshold).

^T denotes the significant relationship between age and PFC connectivity strength even after controlling for cortical thickness of the corresponding regions.