Table 2. Several histological parameters in MN cases with or without FSGS lesion.
MN with | MN without | P | |
---|---|---|---|
FSGS lesion | FSGS lesion | ||
VEGF expression (index)** | 1.2 ± 0.7 | 1.4 ± 0.9 | 0.6 |
global sclerotic glomeruli (%)* | 11.4 ± 10.8 | 7.2 ± 7.1 | 0.1 |
interstitial fibrosis (index)** | 1.2 ± 0.5 | 1.0 ± 0.6 | 0.06 |
arteriosclerosis (index)** | 1.7 ± 0.8 | 1.8 ± 0.7 | 0.82 |
* Student’s t-test
** Mann-Whitney U test
Staining intensity of VEGF based on immunohistochemical study was scored semiquantitatively (see Materials and Methods).
Interstitial fibrosis and arteriosclerosis were also graded semiquantitatively (see Materials and Methods).