Figure 2. The effect of gut microbiota on infection with C. rodentium.
(A) The relative quantity of bacteria from the Firmicutes phylum, the Bacteroidetes phylum and the Proteobacteria phylum in the feces of WT and VDR KO mice. (B) The relative total amount of universal 16S rDNA in the feces of WT and VDR KO mice before and after ABX treatment. The values were normalized to the fecal weight. (C) Shedding of C. rodentium in the feces of WT, VDR KO, ABX WT and ABX VDR KO mice. (D) The survival rate of the WT, VDR KO, ABX WT and ABX VDR KO mice following infection with C. rodentium. Data shown is mean ± SEM using n=4–10 mice/group. Two-tailed student’s t tests (A), two-way ANOVA with Bonferroni post-hoc tests (B, C), and log-rank test (D), *P <0.05. Values (B and C) without a common letter are significantly different.