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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: J Invest Dermatol. 2014 Oct 15;135(6):1638–1648. doi: 10.1038/jid.2014.450

Figure 2.

Figure 2

Time and dose-dependent changes in CORT production and skin histological evaluation after UVB radiation.

Dose- (a) and time- (b) dependent increases in CORT production after UVB exposure in C57BL6 shaved mouse skin, evaluated with ELISA. A dose-dependent histological evaluation observed 12 h after UVB irradiation with a dose of 100 and 400 mJ/cm2 (c). Time-dependent histological changes evolved after 1, 3 and 6 h followed by UVB exposure of 400 mJ/cm2 (d). H&E staining on formalin fixed and paraffin embedded skin representative sections. Data were analyzed using Student’s t-test, * p<0.05, ** p<0.01, and *** p<0.001 or one-way ANOVA, ## p<0.01; ### p<0.001. Scale bar = 100 µm.