Table 2.
Case | N-terminal Fusion Partner (Transcript ID) | Genomic location | Intron of N-terminal partner rearranged | Location of rearrangement in ALK (NM_004304) | Classification of Structural Rearrangement | Reads Supporting Fusion | Average Coverage |
---|---|---|---|---|---|---|---|
11 | GTF3C2 (NM_001521) | 2p23.3 | 1 | exon 18 | double minute | 760 | 330 |
19 | NPM1 (NM_002520) | 5q35.1 | 4 | intron 20 | reciprocal translocation | 26 | 244 |
29 | CLIP1 (NM_002956) | 12q24.31 | 13 | intron 20 | NOS | 28 | 205 |
31 | TPR (NM_003292) | 1q31.1 | 4 | intron 20 | complex | 33 | 283 |
NOS: not otherwise specified