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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: J Pathol. 2015 Feb 19;236(1):30–40. doi: 10.1002/path.4508

Figure 4. PTEN regulates Rac1/Cdc42 and RhoA activities in mouse podocyte cultures.

Figure 4

A: The activities of small GTPases (Rac1, Cdc 42 and RhoA) in differentiated mouse podocytes were evaluated with or without BpV (100 ug/ml) treatment by Western blot after a pull-down assay (n=3 in each group, *<0.05).

B: Rac1, Cdc 42 and RhoA activities were evaluated by Western blot analysis after treatment with Ang II (ug/ml) for 24 h.

C: After exposure to TGF-β1 for 16 h, Rac1, Cdc 42 and RhoA activities were assessed by Western blotting. For the analysis of forced expression of PTEN, differentiated mouse podocytes were infected with adenoviruses: Ad-PTEN or Ad-β-gal (as control).