Skip to main content
. 2015 Mar 24;20(1):707–719. doi: 10.2119/molmed.2014.00231

Figure 1.

Figure 1

Mo-DCs derived from PRDM1 IBD risk allele carrier have low levels of Blimp-1 and increased proinflammatory cytokine expression. (A) Blimp-1 expression was measured by qPCR of Mo-DCs differentiated from monocytes carrying CC nonrisk (control) or TT risk (carrier) of rs6911490. Each dot represents an individual person and the bar represents the mean (n = 7). (B) Mo-DCs differentiated from either control or carrier monocytes as indicated in (A) were incubated with or without 1 μg/mL LPS for 18 h. After stimulation, supernatant was harvested and the levels of cytokines were measured with a human 9-flex multiplex cytokine kit from MSD. Each dot represents an individual person and the bar represents the mean (n = 7).