Figure 3.

Reduced TG hydrolase activity and fatty acid oxidation in the heart of mCgi58-KO mice. A, Cardiac TG hydrolase activity (n = 5). B, Western blottings of ATGL. GAPDH was used as a loading control. C, Relative mRNA levels in the ventricular tissue of control and mCgi58-KO mice (n = 4). D, Cardiac fatty acid oxidation activity (n = 5). E, Cardiac contents of total acyl-carnitine (AC) and AC species (n = 6). All tissue samples were collected from 4-hour-fasted mice fed the HFD for 12 weeks. *, P < .05; **, P < .01.