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. 2015 Mar 9;156(5):1648–1658. doi: 10.1210/en.2014-1892

Figure 4.

Figure 4.

mCgi58-KO mice have increased glucose tolerance and insulin sensitivity. A, GTT in mCgi58-KO mice (n = 7) and control littermates (n = 6) on HFD for 8 weeks. B, ITTs in mCgi58-KO mice (n = 12) and control littermates (n = 12) on HFD for 10 weeks. C, Basal glucose uptake in heart (n = 5) and soleus (n = 3). D, Cardiac and soleus mRNA levels of GLUTs in 4-hour-fasted mice fed the HFD for 12 weeks (n = 4). E, Western blot analysis (left panel) of Akt phosphorylation at serine 473, total Akt, and GAPDH (as loading controls). Right panel, Densitometry analysis of the blots. *, P < .05 and **, P < .01.