Fig. 5.

Inflammatory profile of muscle surrounding surgical hip in THA patients classified as muscle inflammation susceptibility positive vs. negative [MuIS⁽⁻⁾ vs. MuIS⁽⁺⁾]. A: THA patients dichotomized into MuIS⁽⁻⁾ vs. MuIS⁽⁺⁾ based on TWEAK-R gene expression. TWEAK-R expression was 5-fold higher in MuIS⁽⁺⁾ than both CON and MuIS⁽⁻⁾. B: muscle expression profile of proteolytic (MuRF1 and atrogin-1) and inflammatory (IL-6, IL-6R, TNF, TNF-R, and TWEAK) genes in MuIS⁽⁻⁾ and MuIS⁽⁺⁾ relative to the CON group (dotted line). Values are means ± SD. *Different from CON, P < 0.05. †Different from MuIS⁽⁻⁾, P < 0.05.