Table 3.
ANOVA of T − C differences from 0 and T/C fractional excretion ratio from 1
| T − C Excretion Difference |
T/C FE Ratio |
|||
|---|---|---|---|---|
| Basal | Acid load | Basal | Acid load | |
| Arterial pH | 0.13 ± 0.04 | −0.04 ± 0.04* | ||
| Adjusted pH | 0.17 ± 0.04 | −0.03 ± 0.03* | ||
| HCO3−, μmol/min | 15 ± 4 | 4 ± 4 | 3 ± 0.9 | 1.5 ± 0.8 |
| Flow, ml/min | 0.5 ± 0.07 | 0.18 ± 0.07*# | — | |
| K, μeq/min | 16 ± 2 | −0.3 ± 2*# | ||
| Cl, μeq/min | 65 ± 10 | 15 ± 9*# | 3.3 ± 0.7 | 2.2 ± 0.6# |
| Sulfate, μeq/min | 2.9 ± 0.5 | 0.4 ± 0.5*# | 1.7 ± 0.2 | 1.3 ± 0.1# |
| Ca, μg/min | 25 ± 5 | −3 ± 4* | 3.1 ± 0.6 | 2 ± 0.6# |
| Mg, μg/min | 28 ± 5 | 4 ± 4* | 2.2 ± 0.2 | 1.4 ± 0.2#* |
| Na, μeq/min | 65 ± 10 | 14 ± 9* | 5 ± 2 | 3 ± 1# |
| Phosphate, μg/min | 0.6 ± 1 | −2 ± 1 | 1.15 ± 0.09 | 0.99 ± 0.08 |
| Oxalate, μg/min | 2.5 ± 0.8 | −0.44 ± 0.8*# | 1.14 ± 0.06 | 1.11 ± 0.06 |
| Urate, μg/min | 0.1 ± 0.2 | −0.3 ± 0.2 | 1.3 ± 0.1 | 1 ± 0.1 |
| CCr, ml/min | 1 ± 1 | −1 ± 1 | ||
| NH4, μmol/min | 0.04 ± 1 | 0.7 ± 0.9 | ||
| FE lithium | 1.454 ± 0.167 | 1.187 ± 0.129 | ||
| CH2O, ml/min | −0.036 ± 0.024 | 0.075 ± 0.023* | ||
| [Na+K], mmol/l | 7 ± 3 | −4 ± 3* | ||
| Urea, μmol/min | 12 ± 3 | 2 ± 3* | ||
| Urea, mmol/l | −29 ± 4 | −19 ± 4 | ||
Values are ANOVA means ± SE for basal and acid load (NH4Cl) conditions adjusted for days since shock wave lithotripsy (SWL) treatment except arterial pH, which is adjusted for arterial pH measured before and during the acid load. FE, fractional excretion; CH2O, free water clearance. Bold, adjusted mean value ≠0 for differences, ≠1 for ratios.
*
Differs from basal, P < 0.05.
#
, Slope dependence on time from SWL, P < 0.05 (# is placed with acid load values but applies to both conditions in the ANOVA model).