Fig. 1.
Effects of extracellular Ca2+ depletion or high Ca2+ on flow-induced changes in fluid (A), sodium (B), bicarbonate (C), and chloride (D) absorption (Jv, JNa, JHCO3 and JCl) in mouse proximal tubules. Jv, JNa, JHCO3, and JCl were measured at low and high perfusion rates in the control (1.2 mM Ca2+), absence of Ca2+ (0 mM Ca2++EGTA), and high Ca2+ (5 mM Ca2+) group, respectively. *P < 0.05, compared with low flow rates in the same group. †P < 0.05, compared with the control at the similar flow rate.