Flow-induced changes in sodium (JNa; A), bicarbonate (JHCO3; B), and chloride (JCl; C), reabsorption, and cell volume (D) under low and high perfusion rates in proximal tubules in the absence or presence of Ca2+ inhibitors and in low and high Ca2+ in the luminal perfusate. % Change is the percent differences from low flow rate of JNa, JHCO3, and JCl shown in Table 2, Table 3, and Table 4, respectively. *P < 0.05, compared with the change in control group.