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Effect of ANG II on intracellular cAMP levels and PKA activity in NRICs. A: ANG II stimulated intracellular cAMP levels in NRICs. *P < 0.05 vs. normal. Data are presented as means ± SE, n = 6. B: ANG II stimulated an increase in PKA activity compared with basal, which is prevented by ARB (losartan). *P < 0.05 vs. basal (control). #P < 0.05 vs. basal. Data are presented as means ± SE, n = 6.
