Table 2.

Susceptibility and FIC values of two clinical cystic fibrosis isolates of P. aeruginosa isolates tested with manuka honey and either tobramycin or colistin

Antibiotic	Pseudomonas aeruginosa reference number	Test method	MIC (µg/ml) antibiotic		FIC antibiotic
			Alone	With MH
Colistin	867	Broth dilution	0.5	0.25	0.5
		E strip	0.38	0.19	0.5
Tobramycin	867	Broth dilution	128	128	1
		E strip	32	32	1
Colistin	1099	Broth dilution	16	4	0.25
		E strip	0.19	0.125	0.66
Tobramycin	1099	Broth dilution	16	0.5	0.03
		E strip	2	0.5	0.25

1 % (w/v) below MIC was used in synergy tests. The FIC values seen were consistent across the methods used

FIC values are in bold

MH manuka honey