Table 1.

Characteristics of the participants of the DIAN study.

Variables	Mutation carriers (MCs) (N = 183)	Noncarriers (NCs) (N = 117)	P value
Age (years)	39.1 ± 10.2	39.6 ± 10.3	0.6771∗
Gender (M/F)	81/102	47/70	0.485∗∗
Education level (years)	13.9 ± 2.7	14.6 ± 2.7	0.0343∗
CDR global	0.3 ± 0.6	0.03 ± 0.1	<0.0001∗
CDR sum of boxes	1.64 ± 3.2	0.1 ± 0.2	<0.0001∗
CDR 0 (number)	107	109	0.892∗∗
CDR 0.5 (number)	48	8	<0.0001∗∗
CDR ≥ 1 (number)	28	0	n.a.
Logical memory, delayed recall (percentile)	38.5 ± 36.8	60.9 ± 31.8	<0.0001∗
MMSE	26.8 ± 7.5	29.03 ± 1.3	<0.0001∗
GDS	3.8 ± 11.2	1.3 ± 1.6	<0.0001∗

^∗Mann-Whitney U test; ^∗∗Chi-square test; CDR denotes Clinical Dementia Rating Scale; M denotes male and F denotes female; MMSE denotes Mini-Mental Status Examination; GDS denotes Geriatric Depression Scale; age, education levels, CDR sum of boxes, MMSE, logical memory, and GDS scores are displayed in mean and standard deviation.