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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Pancreas. 2015 May;44(4):636–647. doi: 10.1097/MPA.0000000000000308

Figure 7. Metformin modulated mRNA expression of the angiogenic genes in pancreatic tumors.

Figure 7

(A–C) Relative mRNA expression of VEGFα (A), TSP-1 (B) and PAI-1 (C) in pancreatic tumors. Values are expressed as fold of the saline-treated control and are means ± SEM, n = 9 or 10 means of triplicate measures. No statistically significant changes of mRNA expression of VEGFα, TSP-1 and PAI-1 were observed in metformin treated groups (Met_1wk and Met_3wk), compared to the untreated control.