TABLE 3.

Survival patterns for selected transposon mutants in mouse models of bubonic and pneumonic plague

Clonea	Gene locus	% of mice surviving postinfection withb:
		∼8 LD50 s.c. on day:			12 LD50 i.n. on day:
		7	14	21	3	9
WT CO92		40	0	0	0	0
15-F2	YPPCP1.07	100	100	80	60	0
19-F7	Unconfirmed	100	80	80	80	0
29-F7	YPO2468	60	60	60	80	40
2-H3	YPO1717	80	60	60	20	0
39-A7	YPO3319	60	60	60	80	0
39-G4	YPMT1.80c	100	40	40	20	0
42-B8	YPO2500	100	100	100	NTc	NTc
44-B5	YPO0498	80	60	60	100	40
44-F11	YPO3603	80	60	60	NTc	NTc
45-B9	YPO2884	100	80	60	100	100
47-F10	Unconfirmed	80	80	80	60	0
47-G5	YPO3164	100	80	80	20	0
48-G1	PMT1 Caf1R	100	100	100	100	20
49-B1	YPO1484	80	60	60	100	100
52-B1	YPO3248	80	60	60	100	80
52-B5	Intergenic, YPO0093-YPO0094	60	60	20	100	80
53-C3	YPO1616	80	80	80	100	100
53-F10	YPO1995	100	100	100	100	0
53-G5	YPO0815	100	60	60	100	100
54-F6	Intergenic, YPO1119-YPO1120	100	100	100	100	60

^aClone identifiers comprise the signature tag number and the alphanumeric of an individual mutant containing that signature.

^bs.c., subcutaneous; i.n., intranasal.

^cNT, not tested for signature-tagged mutants, but an isogenic mutant was prepared and examined.