FIG 4.

Genetic locus map of the 94-kb GI-VR50-pheV island and adjacent kps capsular biosynthesis gene cluster from E. coli VR50 (drawn to scale). The arrows showing genes are colored according to the modules shown in Fig. 5. IntP-like integrase genes, the pheV tRNA gene, and pheV repeats (phe′V and phe′V -2) are colored black. Insertion sequences are shown as white arrows and may contain more than one coding sequence (CDS). Direct repeats (172 nt) are shown as boxes adjacent to phe′V and phe′V -2. Degenerate or truncated genes or insertion sequences are labeled with an apostrophe. GI-VR50-pheV is a composite genomic island formed from two independent integrase-mediated insertions.