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. 2015 Feb 15;7(2):175–193.

Table 2.

Regulators of EZH2 transcription

Factor/Pathway Cancer type References
MYC Prostate [69]
ETS/ERG Prostate [70]
E2F (pRB-E2F pathway) Breast [32]
Lung [68]
Bladder [66,67]
ELK1 (MEK-ERK pathway) Breast [65,76]
ATAD2/ANCCA Breast [73]
NF-YA Ovarian [71]
STAT3 Colorectal [72]
BRAF (V600E) Melanoma [75]
EWS-FLI1 Ewing’s sarcoma [74]
HIF1α (Hypoxia) Breast [76]