Table 2.
SNP | Genetic model | Crude HR (95% CI) | P value | Adjusted HR (95% CI)a | P value |
---|---|---|---|---|---|
rs71428439 | AA | 1 | 1 | ||
AG | 1.197 (0.904-1.584) | 0.209 | 1.168 (0.874-1.560) | 0.295 | |
GG | 1.203 (0.833-1.737) | 0.324 | 1.146 (0.784-1.676) | 0.482 | |
Dominant | 1.198 (0.920-1.561) | 0.179 | 1.163 (0.884-1.529) | 0.280 | |
Recessive | 1.088 (0.783-1.512) | 0.616 | 1.048 (0.747-1.472) | 0.785 | |
Additive | 1.112 (0.933-1.325) | 0.235 | 1.085 (0.905-1.301) | 0.377 | |
rs2910164 | GG | 1 | 1 | ||
CG | 1.156 (0.804-1.661) | 0.434 | 1.164 (0.799-1.696) | 0.430 | |
CC | 1.069 (0.803-1.423) | 0.649 | 1.106 (0.824-1.148) | 0.504 | |
Dominant | 1.092 (0.8833-1.430) | 0.524 | 1.119 (0.848-1.478) | 0.427 | |
Recessive | 1.111 (0.808-1.527) | 0.518 | 1.095 (0.787-1.524) | 0.591 | |
Additive | 1.074 (0.898-1.285) | 0.433 | 1.081 (0.899-1.300) | 0.406 | |
rs3746444 | AA | 1 | 1 | ||
AG | 0.885 (0.662-1.183) | 0.409 | 0.932 (0.691-1.256) | 0.643 | |
GG | 1.818 (1.130-2.925) | 0.014 | 1.913 (1.162-3.152) | 0.011 | |
Dominant | 1.003 (0.770-1.307) | 0.982 | 1.050 (0.798-1.381) | 0.728 | |
Recessive | 1.885 (1.180-3.011) | 0.008 | 1.954 (1.197-3.192) | 0.007 | |
Additive | 1.113 (0.899-1.378) | 0.326 | 0.867 (0.695-1.082) | 0.207 | |
rs6505162 | CC | 1 | |||
AC | 1.007 (0.767-1.323) | 0.959 | 0.983 (0.741-1.304) | 0.904 | |
AA | 1.001 (0.528-1.897) | 0.998 | 1.036 (0.522-2.057) | 0.920 | |
Dominant | 1.007 (0.775-1.308) | 0.961 | 0.987 (0.752-1.296) | 0.927 | |
Recessive | 0.999 (0.530-1.880) | 0.997 | 1.041 (0.527-2.055) | 0.908 | |
Additive | 1.004 (0.805-1.253) | 0.969 | 0.995 (0788-1.257) | 0.968 | |
rs2168518 | CC | 1 | 1 | ||
CT | 1.287 (0.988-1.677) | 0.061 | 1.345 (1.022-1.770) | 0.034 | |
TT | 1.721 (1.101-2.689) | 0.017 | 1.714 (1.077-2.729) | 0.023 | |
Dominant | 1.350 (1.051-1.736) | 0.019 | 1.401 (1.079-1.819) | 0.011 | |
Recessive | 1.545 (1.006-2.374) | 0.047 | 1.503 (0.962-2.349) | 0.074 | |
Additive | 1.302 (1.074-1.579) | 0.007 | 1.323 (1.084-1.615) | 0.006 |
adjusted for age, sex, DM, MI, SBP, DBP, TC, TG, HDL, LDL and FPG.