Figure 2.
Propionic acid breakdown pathway and Vitamin B12. C. elegans genes that are associated with each reaction are shown in italics. Human orthologs of selected genes (bold italics) are provided in Table 1. Dashed arrows indicate pathways not shown in detail. MCM, Methylmalonyl-CoA mutase; ppcoa, propionyl CoA; mmcoa, methylmalonyl CoA; succoa, succinyl CoA; Cbl, cobalamin; adoCbl, adonesylcobalamine.