Table 1.
Clinical and biochemical characteristics in cluding metabolic components and lipid measures in participant with and without the carotid atherosclerosis in both genders
| Variables | Men | Women | ||||
|---|---|---|---|---|---|---|
| Carotid atherosclerosis (−); n = 1245 | Carotid atherosclerosis (+); n = 247 | P -value | Carotid atherosclerosis (−); n = 309 | Carotid atherosclerosis (+); n = 62 | P -value | |
| Age (ys) | 45.14 ± 0.23 | 53.95 ± 0.58 | <0.001 | 49.61 ± 0.50 | 58.47 ± 1.17 | <0.001 |
| SBP (mm Hg) | 137.83 ± 0.31 | 142.69 ± 1.01 | <0.001 | 137.28 ± 0.61 | 142.52 ± 1.55 | <0.001 |
| DBP (mm Hg) | 80.10 ± 0.27 | 90.16 ± 0.73 | <0.001 | 86.40 ± 0.53 | 88.53 ± 1.39 | <0.001 |
| BMI (kg/m2) | 25.75 ± 0.08 | 25.63 ± 0.17 | 0.544 | 24.26 ± 0.17 | 25.23 ± 0.39 | 0.021 |
| FPG (mmol/L) | 5.70 ± 0.03 | 5.96 ± 0.10 | 0.016 | 5.62 ± 0.06 | 5.65 ± 0.09 | 0.848 |
| FINS (pmol/L) | 70.01 ± 1.10 | 60.49 ± 2.21 | <0.001 | 62.99 ± 1.75 | 72.06 ± 4.63 | 0.041 |
| HOMA-IR | 2.58 ± 0.05 | 2.34 ± 0.11 | 0.034 | 2.28 ± 0.07 | 2.62 ± 0.18 | 0.056 |
| TC (mmol/L) | 5.28 ± 0.03 | 5.46 ± 0.06 | 0.007 | 5.38 ± 0.05 | 5.74 ± 0.12 | 0.005 |
| HDL-C (mmol/L) | 1.36 ± 0.01 | 1.38 ± 0.02 | 0.284 | 1.64 ± 0.02 | 1.53 ± 0.04 | 0.01 |
| non-HDL-C/HDL-C | 2.97 ± 0.02 | 3.06 ± 0.06 | 0.149 | 2.37 ± 0.04 | 2.82 ± 0.08 | <0.001 |
| LDL-C (mmol/L) | 3.44 ± 0.02 | 3.55 ± 0.05 | 0.041 | 3.29 ± 0.04 | 3.65 ± 0.09 | 0.001 |
| TG (mmol/L) | 2.31 ± 0.04 | 2.13 ± 0.08 | 0.054 | 1.72 ± 0.04 | 2.14 ± 0.13 | <0.001 |
| ApoAΙ (g/L) | 1.38 ± 0.01 | 1.40 ± 0.01 | 0.321 | 1.54 ± 0.01 | 1.51 ± 0.02 | 0.26 |
| ApoB (g/L) | 1.17 ± 0.01 | 1.25 ± 0.02 | <0.001 | 1.13 ± 0.02 | 1.27 ± 0.04 | 0.001 |
| ApoB/apoAΙ | 0.85 ± 0.01 | 0.91 ± 0.02 | 0.001 | 0.75 ± 0.01 | 0.85 ± 0.03 | 0.001 |
| CRP (mg/L) | 5.35 ± 0.12 | 5.67 ± 0.48 | 0.363 | 5.34 ± 0.21 | 4.57 ± 0.35 | 0.117 |
| HCY (μmol/L) | 11.16 ± 0.15 | 11.6 ± 0.29 | 0.186 | 8.28 ± 0.18 | 9.76 ± 0.38 | 0.001 |
| GGT (U/L) | 61.54 ± 1.60 | 54.47 ± 3.72 | 0.074 | 23.69 ± 1.13 | 30.95 ± 3.86 | 0.075 |
| UA (μmol/L) | 371.29 ± 2.15 | 360.94 ± 4.51 | 0.048 | 257.46 ± 3.07 | 283.81 ± 7.56 | 0.001 |
| Current smoker(%) | 41.5 | 39.7 | >0.05 | 0.6 | 0 | >0.05 |
SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; FPG: fasting plasma glucose; FINS: fasting insulin; HOMA-IR: homeostasis model assessment of insulin resistance; TC: total cholesterol; HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol; non-HDL-C: non-high density lipoprotein cholesterol; TG: triglycerides; ApoAΙ: apolipoprotein AΙ; ApoB: apolipoprotein B; CRP: C-reactive protein; HCY: Homocysteine; GGT: gamma-glutamyl transpeptidase; UA: uric acid; Carotid atherosclerosis(+): CIMT was ≥ 0.9 mm; Carotid atherosclerosis(−): CIMT was < 0.9 mm.