Table 1.
Patient Demographic, Clinical, and Pathological Characteristics by RAI Therapy (1998–2006)
| No RAI |
RAI |
P Value | |||
|---|---|---|---|---|---|
| n | (%) | n | (%) | ||
| Intermediate-risk patients (n = 21 870) | 6452 | (29.5) | 15 418 | (70.5) | |
| Age, y | <.001 | ||||
| <45 (n = 12 612) | 3611 | (56.0) | 9001 | (58.0) | |
| 45–64 (n = 7136) | 2133 | (33.0) | 5003 | (32.0) | |
| ≥65 (n = 2112) | 708 | (11.0) | 1414 | (9.0) | |
| Mean (SD) | 44 | (15.3) | 43 | (14.4) | <.001 |
| Female gender | 4584 | (71.0) | 10 851 | (70.4) | NS |
| Race | <.001 | ||||
| White | 5456 | (86.7) | 13 384 | (88.5) | |
| Black | 391 | (6.2) | 762 | (5.0) | |
| Other | 446 | (7.1) | 978 | (6.5) | |
| Year of diagnosis | <.001 | ||||
| 1998–2000 | 1539 | (23.9) | 3105 | (20.1) | |
| 2001–2003 | 1940 | (30.1) | 4389 | (28.5) | |
| 2004–2006 | 2973 | (46.1) | 7924 | (51.4) | |
| Insurance (n = 21 163) | <.001 | ||||
| Insured | 5810 | (95.5) | 14 613 | (96.9) | |
| Income (n = 20 585) | NS | ||||
| High | 4561 | (74.8) | 10 939 | (75.5) | |
| Education level (n = 20 585) | <.001 | ||||
| High | 2562 | (42.0) | 6484 | (44.8) | |
| Facility type | <.001 | ||||
| Community Cancer Program | 541 | (8.4) | 853 | (5.5) | |
| Comprehensive Community Cancer | 3131 | (48.5) | 7734 | (50.2) | |
| Academic | 2521 | (39.1) | 6455 | (41.9) | |
| Other | 259 | (4.0) | 376 | (2.4) | |
| Facility location | <.001 | ||||
| Northeast | 1945 | (30.1) | 3364 | (21.8) | |
| South | 1846 | (28.6) | 4442 | (28.8) | |
| Midwest | 1470 | (22.8) | 3871 | (25.1) | |
| West | 1193 | (18.5) | 3741 | (24.3) | |
| Charlson-Deyo comorbidity score (n = 13 531)a | NS | ||||
| 0 | 3310 | (88.4) | 8743 | (89.3) | |
| 1 | 368 | (9.8) | 922 | (9.4) | |
| 2 | 65 | (1.7) | 123 | (1.3) | |
| Surgical margins (n = 19 786) | <.001 | ||||
| Positive | 861 | (14.7) | 2658 | (19.1) | |
| Multifocality (n = 10 368)b | <.001 | ||||
| Yes | 1293 | (46.6) | 3878 | (51.1) | |
| Lymph nodes status (n = 21 635) | <.001 | ||||
| Not examined | 1380 | (21.6) | 2611 | (17.1) | |
| Negative | 674 | (10.6) | 1434 | (9.4) | |
| Positive | 4334 | (67.9) | 11 209 | (73.5) | |
| Tumor size, cm (n = 20 662) | <.001 | ||||
| ≤1 | 1129 | (19.0) | 2760 | (19.0) | |
| >1–2 | 1760 | (29.0) | 4609 | (32.0) | |
| >2–3 | 1021 | (17.0) | 2775 | (19.0) | |
| >3–4 | 489 | (8.0) | 1239 | (8.0) | |
| >4 | 1675 | (28.0) | 3205 | (22.0) | |
| Mean (SD) | 3 | (3.1) | 2.7 | (2.9) | <.001 |
| Median (IQR) | 2.2 | (1.3–4.4) | 2 | (1.2–3.8) | |
Abbreviations: IQR, interquartile range; NS, not statistically significant. Values are presented as numbers (percentages) of the given sample size unless otherwise indicated.
a
Variable not collected in NCDB before 2003; values are presented as percentages of the known after 2003.
b
Variable not collected in NCDB before 2004; values are presented as percentages of the known after 2004.